BDBM50050513 (R)-1-((S)-2-amino-3-methylbutanoyl)pyrrolidin-2-ylboronic acid::(S)-2-Amino-1-((R)-2-dihydroxyboron-pyrrolidin-1-yl)-3-methyl-butan-1-one::(S)-2-Amino-3-methyl-2-boronic acid-1-pyrrolidin-1-yl-butan-1-one::Boronic acid derivative::CHEMBL67279::Ketopyrrolidine derivative::Pyrrolidine derivative::US11096924, DASH-inhibitors 2504 C::US11504364, Compound Val-boroPro::US11559537, Compound 2054-Val-boro-Pro::US11707539, Compound 2054
SMILES CC(C)[C@H](N)C(=O)N1CCC[C@H]1B(O)O
InChI Key InChIKey=FKCMADOPPWWGNZ-YUMQZZPRSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 50050513
Affinity DataKi: 0.760nMAssay Description:Inhibition of human recombinant DPP9 expressed in HEK293T cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of human DPP9More data for this Ligand-Target Pair
Affinity DataIC50: 6.80E+3nMAssay Description:Inhibition of human recombinant DPP9 expressed in intact HEK293T cells after 2 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.20nMAssay Description:Inhibition of human DPP9 using H-Gly-Pro-AMC as substrate preincubated for 10 mins prior to substrate addition by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.70E+3nMAssay Description:EnzymesRecombinant human DPPIV (R&D Systems, Cat. No. 1180-SE)Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527)Recombinant human DPP9 (...More data for this Ligand-Target Pair
Affinity DataIC50: 1.60E+7nMAssay Description:EnzymesRecombinant human DPPIV (R&D Systems, Cat. No. 1180-SE)Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527)Recombinant human DPP9 (...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:DPP9 enzymatic activity assay. To assay baseline dipeptidyl peptidase 9 (DPP9) activity, 40 ng of recombinant human DPP9 (rhDPP9) (R&S system, #5419-...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:DPP9 enzymatic activity assay. To assay baseline dipeptidyl peptidase 9 (DPP9) activity, 40 ng of recombinant human DPP9 (rhDPP9) (R&S system, #5419-...More data for this Ligand-Target Pair
Affinity DataIC50: 1.70nMAssay Description:This assay is described in Bachovchin et al. Nature Chemical Biology 10, 656-663 (2014). Briefly, purified enzymes are coupled to Luminex microsphere...More data for this Ligand-Target Pair